Loading... Please wait...

New Product Now Available: Anti-Müllerian Hormone ELISA Assay Kit

Posted by

We at Eagle Biosciences are Proud to Introduce a New ELISA to Our Endocrinology Product Line:

Human Anti-Müllerian Hormone ELISA Assay Kit

What is Anti-Müllerian Hormone (AMH)?

Anti-Müllerian Hormone (AMH) or Müllerian-inhibiting hormone (MIH) is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH expression is critical to sex differentiation at a specific time during fetal development, and appears to be tightly regulated by nuclear receptor SF1, transcription GATA factors, sex-reversal gene DAX1, and follicle-stimulating hormone (FSH). AMH is activated by SOX9 in the Sertoli cells of the male fetus thereby arresting the development of fallopian tubes, uterus, and upper vagina. AMH is also a product of granulosa cells of the preantral and small antral follicles in women. As such, AMH is only present in the ovary until menopause. AMH can serve as a molecular biomarker for relative size of the ovarian reserve and can also be used as a marker for ovarian dysfunction, such as in women with polycystic ovary syndrome (PCOS).

What Makes Eagle Biosciences AMH Assay Different?

Compared to other products on the market, our Anti-Müllerian Hormone ELISA Assay Kit provides a much simpler procedure with less washes and incubation time. Eagle Biosciences Human Anti-Müllerian Hormone ELISA Assay kit is intended for use in the quantitative determination of human Anti-Mullerian Hormone (AMH) levels in serum, EDTA plasma and lithium heparin plasma samples.

Size1x96 wells
Sensitivity0.02 ng/mL
Dynamic Range0.11-20 ng/mL
Incubation Time4.5 hours
Sample TypeSerum/Plasma
Sample Size50 µL

Supporting Resources: 

Broer, S., Broekmans, F., Laven, J. and Fauser, B. (2014). Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications. Human Reproduction Update, 20(5), pp.688-701.

Dewailly, D., Andersen, C., Balen, A., Broekmans, F., Dilaver, N., Fanchin, R., Griesinger, G., Kelsey, T., La Marca, A., Lambalk, C., Mason, H., Nelson, S., Visser, J., Wallace, W. and Anderson, R. (2014). The physiology and clinical utility of anti-Müllerian hormone in women. Human Reproduction Update, 20(3), pp.370-385.

Dumont, A., Robin, G., Catteau-Jonard, S. and Dewailly, D. (2015). Role of Anti-Müllerian Hormone in pathophysiology, diagnosis and treatment of Polycystic Ovary Syndrome: a review. Reproductive Biology and Endocrinology, 13(1).

Eagle Biosciences, Inc.
20A NW Blvd., Suite 112
Nashua, NH 03063
Email: info@eaglebio.com
Toll Free: 866-411-8023
International: +617-419-2019