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All About Endostatin

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What is ENDOSTATIN?

Endostatin is the biologically active 20-kDa C-terminal fragment of collagen XVIII.

Which function does it have?Endostatin is a highly potent inhibitor of angiogenesis: it induces microvascular endothelial cell apoptosis and inhibits endothelial proliferation and angiogenesis.

What is the clinical relevance of Endostatin? Remodelling of the extracellular matrix is present in various types of renal disease e.g. in renal carcinoma and fibrosis. Endostatin is currently being tested as an anti-angiogenic drug.

Endostatin levels are associated with (click here to view summary of studies):


- kidney injury in the elderly
- cardiovascular events and survival in CKD subjects
- kidney disease and mortality in patients with type 2 Diabetes
- Endostatin may improve acute kidney injury risk prediction in critically ill subjects


How can I measure Endostatin?

Endostatin can easily be measured with our highly specific Endostatin ELISAs

Human ENDOSTATIN ELISA

for serum, plasma & urine

sample volume: 10 µl / well

Assay Specifications

Assay Validation Data

Instructions for Use

Mouse/Rat ENDOSTATIN ELISA


for serum and plasma
sample volume: 5 µl / well

Assay Specifications

Assay Validation Data

Instruction for Use

Features and Benefits:

SUPERIOR QUALITY – kits fully validated (internat. quality guidelines)

HIGHLY SPECIFIC KITS – utilizing characterized antibodies

EASY handling all reagents included in the kits

LOW sample volume

FAST – results in 3 hours

Get a 20% Discount on Endostatin Kits*

*Promotion is valid through June 30, 2017.



Eagle Biosciences, Inc.
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Nashua, NH 03063
Email: info@eaglebio.com
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